In my personal experience with cnc machines, the industrial controls are more robust and reliable but not as user friendly.
I have had 2 Busellatos a Giben panel saw a pair of Komos and a pair of Onsruds in my care over the last 16 years. The short version is that the Giben with it's DOS control on a 386 just outlived it's parts availability for the pc, couldn't find the hardware for the pc anymore to keep it running. The techs at Giben were too new to know if very well either, not their fault it was a 1996 machine.
The busellatos had their own quirks, they were windows pc driven machines that the last one we had would boot up in Italian app once a month. It was nice for networking and file sharing etc, but the control didn't have the reliability that I expect out of a $100k machine.
The Komo's are still running and they are 1991 and 1992 machines with a Fanuc OM-C control. They are capable of the same things the new ones are, just harder to learn it. They also have a memory limit that the pc machines do not. If you plan to surface machine alot or carve/engrave alot, then look for a newer version with more memory. The OM is limited on its internal memory but I can DNC code and it works fine. They are still going strong and do not have any quirks. I have my own shop and that is what I bought was an old 'obsolete' komo 3 yrs ago.
The Onsruds I had were both windows based Osai controls and they also had their quirks, I loved that they were very capable and easy to drive, but they still had issues related to using a PC/windows machine to control it. Interesting that they now are offering Fanuc controls....
It depends what you are comfortable with to a point. Many many people absolutely hate the old Fanuc controls because they are a bit of a pain to use, but guess what, they work everytime you turn it on. I look at is as once you learn it, it is not a problem. No, it is not as easy to navigate as a windows machine, but I need a machine that works all the time, not get in a hot job and get the blue screen of death or, "we are unsure, did you reboot it? Try that first" BS, These machines cost too much money to have a flakey pc running them. I also really like the fact that Fanuc is worldwide and their controls are on thousands of machines in every industry out there so online help and parts are more common than say a late 90's Italian proprietary machine that they only made a couple hundred at most.
Also pay attention to the steps required to get from screen to machine, the more proprietary they are the more trouble you will have when the system is old. If the system hinges on a 3rd party software to post the code and that guy is working out of his basement and kicks the bucket, you are out of luck if you need help.
There is something to be said about using a very popular software and machine. You can usually get alot more info and help from other users vs being stuck with the dealer only.
Good luck